Symptoms

I am working full time, and over the past month I am having stiffness in my lower back I get weird tingling sensations in my stomach that seem to wrap around to my lower back, I do my exercises and it is the worst in the morning, I find showering helps and stretching. The spasms are not horrible but I can sense them. the past few weeks I am having pain in my knees and they were both replaced lol so I'm guessing its nerve pain . I am only on Uplinza had 1st infusion in March and 2ns one end of Sept, I am working hard to stick working fulltime as long as possible. I live in Florida and really would love to get involved with clinical trial at Mayo clinic. Anyone have success with clinical trials ?